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stat.ME2026
Multi-Objective Composite Longitudinal Biomarker Scores for Improved Cancer Risk Assessment
Bitan Sarkar, Ana Maria Kenney, James P. Long +4
Repeated blood-based biomarker measurements can improve cancer risk assessment by capturing longitudinal changes missed by single-time-point analyses. Parametric Empirical Bayes (P…
stat.ME2026
MR-CCC: Bayesian Mendelian Randomization for Causal Cell--Cell Communication
Bitan Sarkar, Yang Ni
Cell--cell communication (CCC) is commonly inferred from ligand--receptor co-expression, an associational paradigm that cannot distinguish causal signaling from shared regulation o…
stat.ME2025
Multivariable Bidirectional Mendelian Randomization via Bayesian Directed Cyclic Graphical Models with Correlated Errors
Bitan Sarkar, Yuchao Jiang, Tian Ge +1
Mendelian randomization (MR) is a pivotal tool in genetics, genomics, and epidemiology, leveraging genetic variants as instrumental variables to infer causal relationships between…