most citedInstructPLM-mu: 1-Hour Fine-Tuning of ESM2 Beats ESM3 in Protein Mutation Predictions

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cs.LG2026

An immune world model for multiscale forecasting and therapeutic hypothesis generation

Taoyong Cui, Xi Wang, Zonghang Li +11

Immune therapies act across cell-intrinsic programs, tissue ecosystems, and patient-specific immune states, yet most predictors address these scales separately. We used a governed…

cs.LG2026

Orthogonal JEPA: Factorized Predictive States for Latent World Models

Taoyong Cui, Pheng Ann Heng, Wanli Ouyang

World models construct latent states that support prediction, planning, and reasoning about an underlying system. Joint-embedding predictive architectures (JEPAs) offer a direct wa…