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cs.LG2025
Glocal Information Bottleneck for Time Series Imputation
Jie Yang, Kexin Zhang, Guibin Zhang +2
Time Series Imputation (TSI), which aims to recover missing values in temporal data, remains a fundamental challenge due to the complex and often high-rate missingness in real-worl…
cs.LG2025
POLO: Preference-Guided Multi-Turn Reinforcement Learning for Lead Optimization
Ziqing Wang, Yibo Wen, William Pattie +6
Lead optimization in drug discovery requires efficiently navigating vast chemical space through iterative cycles to enhance molecular properties while preserving structural similar…
cs.LG2025
Cross-Domain Conditional Diffusion Models for Time Series Imputation
Kexin Zhang, Baoyu Jing, K. Selçuk Candan +4
Cross-domain time series imputation is an underexplored data-centric research task that presents significant challenges, particularly when the target domain suffers from high missi…