1 citations · 1 across the 5 of their papers we have counts for
6 papers
MechPert: Mechanistic Consensus as an Inductive Bias for Unseen Perturbation Prediction
Marc Boubnovski Martell, Josefa Lia Stoisser, Lawrence Phillips +6
Predicting transcriptional responses to unseen genetic perturbations is essential for understanding gene regulation and prioritizing large-scale perturbation experiments. Existing…
Towards Label-Free Biological Reasoning Synthetic Dataset Creation via Uncertainty Filtering
Josefa Lia Stoisser, Lawrence Phillips, Aditya Misra +5
Synthetic chain-of-thought (CoT) traces are widely used to train large reasoning models (LRMs), improving generalization by providing step-level supervision. Yet most approaches re…
Towards Agents That Know When They Don't Know: Uncertainty as a Control Signal for Structured Reasoning
Josefa Lia Stoisser, Marc Boubnovski Martell, Lawrence Phillips +6
Large language model (LLM) agents are increasingly deployed in structured biomedical data environments, yet they often produce fluent but overconfident outputs when reasoning over…
SynthPert: Enhancing LLM Biological Reasoning via Synthetic Reasoning Traces for Cellular Perturbation Prediction
Lawrence Phillips, Marc Boubnovski Martell, Aditya Misra +4
Predicting cellular responses to genetic perturbations represents a fundamental challenge in systems biology, critical for advancing therapeutic discovery and virtual cell modeling…
Modeling Gene Expression Distributional Shifts for Unseen Genetic Perturbations
Kalyan Ramakrishnan, Jonathan G. Hedley, Sisi Qu +5
We train a neural network to predict distributional responses in gene expression following genetic perturbations. This is an essential task in early-stage drug discovery, where suc…
Query, Don't Train: Privacy-Preserving Tabular Prediction from EHR Data via SQL Queries
Josefa Lia Stoisser, Marc Boubnovski Martell, Kaspar Märtens +4
Electronic health records (EHRs) contain richly structured, longitudinal data essential for predictive modeling, yet stringent privacy regulations (e.g., HIPAA, GDPR) often restric…