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cs.LG2025
SafeProtein: Red-Teaming Framework and Benchmark for Protein Foundation Models
Jigang Fan, Zhenghong Zhou, Ruofan Jin +3
Proteins play crucial roles in almost all biological processes. The advancement of deep learning has greatly accelerated the development of protein foundation models, leading to si…
cs.LG2025
Evolutionary Profiles for Protein Fitness Prediction
Jigang Fan, Xiaoran Jiao, Shengdong Lin +5
Predicting the fitness impact of mutations is central to protein engineering but constrained by limited assays relative to the size of sequence space. Protein language models (pLMs…