2 citations · 3 across the 4 of their papers we have counts for
4 papers
scPPDM: A Diffusion Model for Single-Cell Drug-Response Prediction
Zhaokang Liang, Shuyang Zhuang, Xiaoran Jiao +3
This paper introduces the Single-Cell Perturbation Prediction Diffusion Model (scPPDM), the first diffusion-based framework for single-cell drug-response prediction from scRNA-seq…
Evolutionary Profiles for Protein Fitness Prediction
Jigang Fan, Xiaoran Jiao, Shengdong Lin +5
Predicting the fitness impact of mutations is central to protein engineering but constrained by limited assays relative to the size of sequence space. Protein language models (pLMs…
Boltzmann-Aligned Inverse Folding Model as a Predictor of Mutational Effects on Protein-Protein Interactions
Xiaoran Jiao, Weian Mao, Wengong Jin +3
Predicting the change in binding free energy () is crucial for understanding and modulating protein-protein interactions, which are critical in drug design. Due to the scarcit…
Floating Anchor Diffusion Model for Multi-motif Scaffolding
Ke Liu, Weian Mao, Shuaike Shen +4
Motif scaffolding seeks to design scaffold structures for constructing proteins with functions derived from the desired motif, which is crucial for the design of vaccines and enzym…