2 papers
stat.AP2026
How should covariates be handled in randomized trials? Empirical evidence from 50 trials and recommendations for practice
Yulin Shao, Liangbo Lyu, Menggang Yu +1
Background and Objective: Covariate adjustment can improve precision and power in randomized clinical trials and is recommended by major regulatory agencies. However, there is limi…
stat.ME2026
Optimizing precision in stepped-wedge designs via machine learning and quadratic inference functions
Liangbo Lyu, Bingkai Wang
Stepped-wedge designs are increasingly used in randomized experiments to accommodate logistical and ethical constraints by staggering treatment roll-out over time. Despite their po…