2 papers
physics.chem-ph2026
LatentChem: From Textual CoT to Latent Thinking in Chemical Reasoning
Xinwu Ye, Yicheng Mao, Yuxuan Liao +16
Current chemical large language models (LLMs) predominantly rely on explicit Chain-of-Thought (CoT) to solve complex reasoning problems. However, forcing nonverbal tacit chemical l…
q-bio.BM2025
RiboPO: Preference Optimization for Structure- and Stability-Aware RNA Design
Minghao Sun, Hanqun Cao, Zhou Zhang +10
Designing RNA sequences that reliably adopt specified three-dimensional structures while maintaining thermodynamic stability remains challenging for synthetic biology and therapeut…