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cs.LG2025
Relaxed Sequence Sampling for Diverse Protein Design
Joohwan Ko, Aristofanis Rontogiannis, Yih-En Andrew Ban +2
Protein design using structure prediction models such as AlphaFold2 has shown remarkable success, but existing approaches like relaxed sequence optimization (RSO) rely on single-pa…
cs.LG2025
Model-Informed Flows for Bayesian Inference
Joohwan Ko, Justin Domke
Variational inference often struggles with the posterior geometry exhibited by complex hierarchical Bayesian models. Recent advances in flow-based variational families and Variatio…