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physics.med-ph2025★ 1 cited
Verification, Validation, and Uncertainty Quantification (VVUQ) of Physiologically Based Pharmacokinetic Models for Theranostic Digital Twins: Towards Reliable Model-Informed Treatment Planning for Radiopharmaceutical Therapies
Nouran R. R. Zaid, Deni Hardiansyah, Tahir Yusufaly +1
Physiologically based pharmacokinetic (PBPK) models provide a mechanistic framework for simulating radiopharmaceutical kinetics and estimating patient-specific absorbed doses (ADs)…
physics.med-ph2025
Quantitative and Computational Radiobiology for Precision Radiopharmaceutical Therapies
Tahir Yusufaly, Hamid Abdollahi, Babak Saboury +1
This article reviews the evolving field of radiobiology, emphasizing the need for advanced multiscale, mechanistic models to optimize radiopharmaceutical therapies (RPT). While the…