4 papers
A Likelihood Ratio Testing Approach for Interval-Censored Data
Yuan Wu, Susan Halabi
Interval-censored data frequently arise in clinical research where event times are only known to fall within specific assessment windows. Although the Cox proportional hazards mode…
Group Sequential Sample Size for Comparing Two Survival Probabilities at a Specific Time Point
Susan Halabi, Lu Liu, Chenxi Yu +1
We propose a novel method that simultaneously determines the sample size for testing two survival probabilities at a pre-specified ltime while guaranteeing type I error control in…
Implementing the principal stratum strategy for intercurrent events with survival outcomes: a tutorial
Xiaoxiao Zhou, Joyce Chen, Pallavi Mishra-Kalyani +5
The International Council for Harmonization (ICH) E9 (R1) addendum provides the estimand framework to formulate treatment effects in a clinical trial. One of the attributes of an e…
Cox Model Predicting Covariate Subject to Right Censoring
Chen-Yen Lin, Susan Halabi, Taehwa Choi
Time-to-event endpoints are frequently used as outcomes in oncology and other disease areas where the outcome of interest may not be observed within a predetermined period. Althoug…