13 citations · 51 across the 15 of their papers we have counts for
16 papers
Phase Separation in a system of Brownian inertial rotors
Lucio Mauro Carenza, Pasquale Digregorio, Massimiliano Semeraro +3
We uncover an emergent phase separation in a system of inertial dumbbells put into persistent rotation by a constant applied torque, breaking chiral symmetry, while interacting wit…
Ordering and Defect Dynamics in Passive and Active Nematopolars
Fabio Aprile, Massimiliano Semeraro, Giuseppe Gonnella
The coexistence of polar and nematic interactions, observed in a broad range of biological and synthetic active systems, gives rise to a rich phenomenology that continues to challe…
Morphology, Polarization Patterns, Compression, and Entropy Production in Phase-Separating Active Dumbbell Systems
Lucio Mauro Carenza, Claudio Basilio Caporusso, Pasquale Digregorio +3
Polar patterns and topological defects are ubiquitous in active matter. In this paper, we study a paradigmatic polar active dumbbell system through numerical simulations, to clarif…
Phase Separation Kinetics in a Polar Active Field Model
Massimiliano Semeraro, Leticia F. Cugliandolo, Giuseppe Gonnella +1
A milestone of phase separation kinetics is the emergence of universal power laws governing the domain growth evolution. We investigate a phase-separating polar acti…
Transverse Self-Propulsion Enhances the Aggregation of Active Dumbbells
Pasquale Digregorio, Daniela Moretti, Claudio Basilio Caporusso +5
We investigate a two-dimensional system of active Brownian dumbbells using molecular dynamics simulations. In this model, each dumbbell is driven by an active force oriented perpen…
Modelling transcriptional silencing and its coupling to 3D genome organisation
Massimiliano Semeraro, Giuseppe Negro, Davide Marenduzzo +1
Timely up- or down-regulation of gene expression is crucial for cellular differentiation and function. While gene upregulation via transcriptional activators has been extensively i…
Work fluctuations for a confined Brownian particle: the role of initial conditions
Giovanni Battista Carollo, Massimiliano Semeraro, Giuseppe Gonnella +1
We study the large fluctuations of the work injected by the random force into a Brownian particle under the action of a confining harmonic potential. In particular, we compute anal…
Fluctuation Theorems for Heat exchanges between passive and active baths
Massimiliano Semeraro, Antonio Suma, Giuseppe Negro
In addition to providing general constraints on probability distributions, fluctuation theorems allow to infer essential information on the role played by temperature in heat excha…
Entropy production of active Brownian particles going from liquid to hexatic and solid phases
Massimiliano Semeraro, Giuseppe Negro, Antonio Suma +2
Due to its inherent intertwinement with irreversibility, entropy production is a prime observable to monitor in systems of active particles. In this numerical study, entropy produc…
A unified-field theory of genome organization and gene regulation
Giuseppe Negro, Massimiliano Semeraro, Perter R Cook +1
Our aim is to predict how often genic and non-genic promoters fire within a cell. We first review a parsimonious pan-genomic model for genome organization and gene regulation, wher…
Work fluctuations for a harmonically confined Active Ornstein-Uhlenbeck Particle
Massimiliano Semeraro, Giuseppe Gonnella, Antonio Suma +1
We study the active work fluctuations of an active Ornstein-Uhlenbeck particle in the presence of a confining harmonic potential. We tackle the problem analytically both for statio…
Diffusion Properties of a Brownian Ratchet with Coulomb Friction
Massimiliano Semeraro, Giuseppe Gonnella, Eugenio Lippiello +1
The motion of a Brownian particle in the presence of Coulomb friction and an asymmetric spatial potential was evaluated in this study. The system exhibits a ratchet effect, i.e., a…
Cluster size determines internal structure of transcription factories in human cells
Massimiliano Semeraro, Giuseppe Negro, Giada Forte +4
Transcription is a fundamental cellular process, and the first step of gene expression. In human cells, it depends on the binding to chromatin of various proteins, including RNA po…
3D polymer simulations of genome organization and transcription across different chromosomes and cell types
Massimiliano Semeraro, Giuseppe Negro, Antonio Suma +2
We employ the diffusing transcription factors model for numerical simulation of chromatin topology conformations and transcriptional processes of human chromatin. Simulations of a…
Large deviations for quadratic functionals of stable Gauss-Markov chains and entropy production
Marco Zamparo, Massimiliano Semeraro
In this paper we establish a large deviation principle for the entropy production rate of possible non-stationary, centered stable Gauss-Markov chains, verifying the Gallavotti-Coh…
Work Fluctuations in the Active Ornstein- Uhlenbeck Particle model
Massimiliano Semeraro, Antonio Suma, Isabella Petrelli +2
We study the large deviations of the power injected by the active force for an Active Ornstein-Uhlenbeck Particle (AOUP), free or in a confining potential. For the free-particle ca…