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20242026
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physics.med-ph2026

A Digital Twin Framework for Adaptive Treatment Planning in Radiotherapy

Chih-Wei Chang, Sri Sai Akkineni, Mingzhe Hu +7

The development of a digital twin (DT) framework for fast online adaptive proton therapy planning in prostate stereotactic body radiation therapy (SBRT) with dominant intraprostati…

physics.med-ph2025

Stereotactic Arrhythmia Radioablation for Refractory Ventricular Tachycardia: A Narrative Review and Exploratory Pooled Analysis of Clinical Outcomes and Toxicity

Keyur D. Shah, Chih-Wei Chang, Sibo Tian +6

Purpose: Stereotactic arrhythmia radioablation (STAR) is a non-invasive salvage therapy for refractory ventricular tachycardia (VT), especially in patients ineligible for catheter…

physics.med-ph2025

A Comparative Dosimetric Study of Proton and Photon Therapy in Stereotactic Arrhythmia Radioablation for Ventricular Tachycardia

Keyur D. Shah, Chih-Wei Chang, Pretesh Patel +8

Purpose: VT is a life-threatening arrhythmia commonly treated with catheter ablation; however, some cases remain refractory to conventional treatment. STAR has emerged as a non-inv…

physics.med-ph2025

An Adaptive Proton FLASH Therapy Using Modularized Pin Ridge Filter

Ahmal Jawad Zafar, Xiaofeng Yang, Zachary Diamond +4

In this paper, we proposed a method to optimize adaptive proton FLASH therapy (ADP FLASH) using modularized pin ridge filters (pRFs) by recycling module pins from the initial plan…

physics.med-ph2024

Using Modularized Pin Ridge Filter in Proton FLASH Planning for Liver Stereotactic Ablative Body Radiotherapy

Chaoqiong Ma, Xiaofeng Yang, Yinan Wang +3

We previously developed a FLASH planning framework for streamlined pin-ridge-filter (pin-RF) design, demonstrating its feasibility for single-energy proton FLASH planning. In this…

physics.med-ph2024

Adaptive Proton Therapy Using CBCT-Guided Digital Twins

Chih-Wei Chang, Zhen Tian, Richard L. J. Qiu +8

This study aims to develop a digital twin (DT) framework to enhance adaptive proton stereotactic body radiation therapy (SBRT) for prostate cancer. Prostate SBRT has emerged as a l…