6 papers
A Digital Twin Framework for Adaptive Treatment Planning in Radiotherapy
Chih-Wei Chang, Sri Sai Akkineni, Mingzhe Hu +7
The development of a digital twin (DT) framework for fast online adaptive proton therapy planning in prostate stereotactic body radiation therapy (SBRT) with dominant intraprostati…
A Large Convolutional Neural Network for Clinical Target and Multi-organ Segmentation in Gynecologic Brachytherapy with Multi-stage Learning
Mingzhe Hu, Yuan Gao, Yuheng Li +10
Purpose: Accurate segmentation of clinical target volumes (CTV) and organs-at-risk is crucial for optimizing gynecologic brachytherapy (GYN-BT) treatment planning. However, anatomi…
Stereotactic Arrhythmia Radioablation for Refractory Ventricular Tachycardia: A Narrative Review and Exploratory Pooled Analysis of Clinical Outcomes and Toxicity
Keyur D. Shah, Chih-Wei Chang, Sibo Tian +6
Purpose: Stereotactic arrhythmia radioablation (STAR) is a non-invasive salvage therapy for refractory ventricular tachycardia (VT), especially in patients ineligible for catheter…
Clinically Interpretable Survival Risk Stratification in Head and Neck Cancer Using Bayesian Networks and Markov Blankets
Keyur D. Shah, Ibrahim Chamseddine, Xiaohan Yuan +8
Purpose: To identify a clinically interpretable subset of survival-relevant features in HN cancer using Bayesian Network (BN) and evaluate its prognostic and causal utility. Method…
A Comparative Dosimetric Study of Proton and Photon Therapy in Stereotactic Arrhythmia Radioablation for Ventricular Tachycardia
Keyur D. Shah, Chih-Wei Chang, Pretesh Patel +8
Purpose: VT is a life-threatening arrhythmia commonly treated with catheter ablation; however, some cases remain refractory to conventional treatment. STAR has emerged as a non-inv…
Photon-Counting CT in Cancer Radiotherapy: Technological Advances and Clinical Benefits
Keyur D. Shah, Jun Zhou, Justin Roper +4
Photon-counting computed tomography (PCCT) marks a significant advancement over conventional energy-integrating detector (EID) CT systems. This review highlights PCCT's superior sp…