67 citations · 70 across the 6 of their papers we have counts for
7 papers
RNADyn: A Benchmark for Generating and Understanding RNA Dynamics
Yiming Huang, Lennart Bastian, Hanqun Cao +2
Ribonucleic acid (RNA) functions through conformational changes that are not fully captured by static structures. However, large-scale standardized RNA dynamics data remain limited…
Lost in Tokenization: Context as the Key to Unlocking Biomolecular Understanding in Scientific LLMs
Kai Zhuang, Jiawei Zhang, Yumou Liu +10
Scientific Large Language Models (Sci-LLMs) have emerged as a promising frontier for accelerating biological discovery. However, these models face a fundamental challenge when proc…
ODesign: A World Model for Biomolecular Interaction Design
Odin Zhang, Xujun Zhang, Haitao Lin +34
Biomolecular interactions underpin almost all biological processes, and their rational design is central to programming new biological functions. Generative AI models have emerged…
RiboPO: Preference Optimization for Structure- and Stability-Aware RNA Design
Minghao Sun, Hanqun Cao, Zhou Zhang +10
Designing RNA sequences that reliably adopt specified three-dimensional structures while maintaining thermodynamic stability remains challenging for synthetic biology and therapeut…
Deep Learning-Based Quasi-Conformal Surface Registration for Partial 3D Faces Applied to Facial Recognition
Yuchen Guo, Hanqun Cao, Lok Ming Lui
3D face registration is an important process in which a 3D face model is aligned and mapped to a template face. However, the task of 3D face registration becomes particularly chall…
Deciphering RNA Secondary Structure Prediction: A Probabilistic K-Rook Matching Perspective
Cheng Tan, Zhangyang Gao, Hanqun Cao +6
The secondary structure of ribonucleic acid (RNA) is more stable and accessible in the cell than its tertiary structure, making it essential for functional prediction. Although dee…
A Survey on Generative Diffusion Model
Hanqun Cao, Cheng Tan, Zhangyang Gao +4
Deep generative models have unlocked another profound realm of human creativity. By capturing and generalizing patterns within data, we have entered the epoch of all-encompassing A…