2 papers
stat.ME2025
Clarifying identification and estimation of treatment effects in the Sequential Parallel Comparison Design
Benjamin Stockton, Michele Santacatterina, Soutrik Mandal +8
Sequential parallel comparison design (SPCD) clinical trials aim to adjust active treatment effect estimates for placebo response to minimize the impact of placebo responders on th…
stat.ME2025
Modern Causal Inference Approaches to Improve Power for Subgroup Analysis in Randomized Controlled Trials
Antonio D'Alessandro, Jiyu Kim, Samrachana Adhikari +3
Randomized controlled trials (RCTs) often include subgroup analyses to assess whether treatment effects vary across pre-specified patient populations. However, these analyses frequ…