3 papers
physics.bio-ph2026
Impact of Oxygen on DNA Damage Distribution in 3D Genome and its Correlation to Oxygen Enhancement Ratio after High-LET Irradiation
Ankang Hu, Wanyi Zhou, Xiyu Luo +2
The variation of the oxygen enhancement ratio (OER) across linear energy transfer (LET) currently lacks a comprehensive mechanistic interpretation and a mechanistic model. Our earl…
physics.med-ph2025
Correlation Between DNA Double-Strand Break Distribution in 3D Genome and Radiation-Induced Cell Death
Ankang Hu, Wanyi Zhou, Xiyu Luo +2
The target theory is the most classical hypothesis explaining radiation-induced cell death, the physical or biological nature of the "target" remains ambiguous. This study hypothes…
physics.med-ph2024
Influencing Factors of the FLASH Effect: Unveiling the Importance of Free Radicals
Yan Zhang, Chenyang Huang, Ankang Hu +10
Purpose: Our aim was to elucidate the critical factors responsible for inducing the FLASH effect, focusing on the role of free radicals through simulation and experimental approach…