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physics.med-ph2026

Quantifying the Impact of Upright Patient Positioning on Cardiac Substructures Using Deep Learning

Nicholas Summerfield, Yuhao Yan, Chase Ruff +4

Upright patient positioners with diagnostic-quality vertical CT at treatment isocenter may improve image-guided radiation therapy (RT). However, cardiac substructure (CS) geometry…

physics.med-ph2026

Bridging cone-beam CT and MRI to stopping power ratio maps: a modality-agnostic Brownian bridge approach to support robust adaptive proton therapy

Yuhao Yan, Qisheng He, Minglei Kang +4

Purpose: Adaptive proton therapy (APT) relies on routine offline CT simulations for updated anatomy. We present a modality-agnostic regularized Brownian bridge (rBBrg) framework to…

physics.med-ph2025

Characterizing the Reliability of a Novel Upright CT for Proton Therapy

Yuhao Yan, Jordan Slagowski, Jessica Miller +4

Purpose: To evaluate reliability of upright CT for proton dose calculation and feasibility of a simplified phantom configuration for accelerated routine QA. Methods: A calibration…

physics.med-ph2025

Technical assessment of a novel vertical CT system for upright radiotherapy simulation and treatment planning

Jordan M. Slagowski, Yuhao Yan, Jessica R. Miller +4

Purpose: To characterize image quality, imaging dose, and dose calculation accuracy for an upright CT scanner with a six-degree-of-freedom patient positioning system. Methods: Imag…

physics.med-ph2025

Evaluation of a Novel Quantitative Multiparametric MR Sequence for Radiation Therapy Treatment Response Assessment

Yuhao Yan, R. Adam Bayliss, Adam R. Burr +5

Purpose: To evaluate a Deep-Learning-enhanced MUlti-PArametric MR sequence (DL-MUPA) for treatment response assessment for brain metastases patients undergoing stereotactic radiosu…