4 papers
Sample Efficient Generative Molecular Optimization with Joint Self-Improvement
Serra Korkmaz, Adam Izdebski, Jonathan Pirnay +5
Generative molecular optimization aims to design molecules with properties surpassing those of existing compounds. However, such candidates are rare and expensive to evaluate, yiel…
seqme: a Python library for evaluating biological sequence design
Rasmus Møller-Larsen, Adam Izdebski, Jan Olszewski +4
Recent advances in computational methods for designing biological sequences have sparked the development of metrics to evaluate these methods performance in terms of the fidelity o…
Mamba Goes HoME: Hierarchical Soft Mixture-of-Experts for 3D Medical Image Segmentation
Szymon Płotka, Gizem Mert, Maciej Chrabaszcz +2
In recent years, artificial intelligence has significantly advanced medical image segmentation. Nonetheless, challenges remain, including efficient 3D medical image processing acro…
ProSpero: Active Learning for Robust Protein Design Beyond Wild-Type Neighborhoods
Michal Kmicikiewicz, Vincent Fortuin, Ewa Szczurek
Designing protein sequences of both high fitness and novelty is a challenging task in data-efficient protein engineering. Exploration beyond wild-type neighborhoods often leads to…