10 citations · 24 across the 11 of their papers we have counts for
5 papers · 1 filter
Entangled Schrödinger Bridge Matching
Sophia Tang, Yinuo Zhang, Pranam Chatterjee
Simulating trajectories of multi-particle systems on complex energy landscapes is a central task in molecular dynamics (MD) and drug discovery, but remains challenging at scale due…
AReUReDi: Annealed Rectified Updates for Refining Discrete Flows with Multi-Objective Guidance
Tong Chen, Yinuo Zhang, Pranam Chatterjee
Designing sequences that satisfy multiple, often conflicting, objectives is a central challenge in therapeutic and biomolecular engineering. Existing generative frameworks largely…
Branched Schrödinger Bridge Matching
Sophia Tang, Yinuo Zhang, Alexander Tong +1
Predicting the intermediate trajectories between an initial and target distribution is a central problem in generative modeling. Existing approaches, such as flow matching and Schr…
Multi-Objective-Guided Discrete Flow Matching for Controllable Biological Sequence Design
Tong Chen, Yinuo Zhang, Sophia Tang +1
Designing biological sequences that satisfy multiple, often conflicting, functional and biophysical criteria remains a central challenge in biomolecule engineering. While discrete…
Gumbel-Softmax Flow Matching with Straight-Through Guidance for Controllable Biological Sequence Generation
Sophia Tang, Yinuo Zhang, Alexander Tong +1
Flow matching in the continuous simplex has emerged as a promising strategy for DNA sequence design, but struggles to scale to higher simplex dimensions required for peptide and pr…