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cs.LG2025
Multiscale Grassmann Manifolds for Single-Cell Data Analysis
Xiang Xiang Wang, Sean Cottrell, Guo-Wei Wei
Single-cell data analysis seeks to characterize cellular heterogeneity based on high-dimensional gene expression profiles. Conventional approaches represent each cell as a vector i…
q-bio.MN2025
Computational Drug Repurposing for Alzheimer's Disease via Sheaf Theoretic Population-Scale Analysis of snRNA-seq Data
Sean Cottrell, Seungmin Yoon, Xiaoqi Wei +2
Single-cell and single-nucleus RNA sequencing (scRNA-seq /snRNA-seq) are widely used to reveal heterogeneity in cells, showing a growing potential for precision and personalized me…