3 papers
cond-mat.stat-mech2025
Stochastic Thermodynamics of Cooperative Biomolecular Machines: Fluctuation Relations and Hidden Detailed Balance Breaking
D. Evan Piephoff, Jianshu Cao
We examine a biomolecular machine involving a driven, observable process coupled to a hidden process in a kinetically cooperative manner. A stochastic thermodynamics framework is e…
physics.bio-ph2025
First-Passage Time Fluctuation Theorem and Thermodynamic Bound in Cooperative Biomolecular Networks
D. Evan Piephoff, Jianshu Cao
Using a pathway analysis technique, a dynamic fluctuation relation is derived for a kinetically cooperative biomolecular machine (e.g., an enzyme or a motor protein). This new rela…
physics.bio-ph2013
Generic Schemes for Single Molecule Kinetics 2: Information Content of the Poisson Indicator
Thomas Avila, D. Evan Piephoff, Jianshu Cao
Recently, we described a pathway analysis technique (paper 1) for analyzing generic schemes for single-molecule kinetics based upon the first-passage time distribution. Here, we em…