18 citations · 19 across the 6 of their papers we have counts for
6 papers
Quantifying the Spatiotemporal Dynamics of Engineered Cardiac Microbundles
Hiba Kobeissi, Samuel J. DePalma, Javiera Jilberto +3
Brightfield time-lapse imaging is widely used in cardiac tissue engineering, yet the absence of standardized, interpretable analytical frameworks limits reproducibility and cross-p…
SarcGraph for High-Throughput Regional Analysis of Sarcomere Organization and Contractile Function in 2D Cardiac Muscle Bundles
Saeed Mohammadzadeh, Yao-Chang Tsan, Aaron Renberg +3
Timelapse images of human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) provide rich information on cell structure and contractile function. However, it is chall…
MicroBundlePillarTrack: A Python package for automated segmentation, tracking, and analysis of pillar deflection in cardiac microbundles
Hiba Kobeissi, Xining Gao, Samuel J. DePalma +8
Movies of human induced pluripotent stem cell (hiPSC)-derived engineered cardiac tissue (microbundles) contain abundant information about structural and functional maturity. Howeve…
MicroBundleCompute: Automated segmentation, tracking, and analysis of subdomain deformation in cardiac microbundles
Hiba Kobeissi, Javiera Jilberto, M. Çağatay Karakan +9
Advancing human induced pluripotent stem cell derived cardiomyocyte (hiPSC-CM) technology will lead to significant progress ranging from disease modeling, to drug discovery, to reg…
A Data-Driven Computational Model for Engineered Cardiac Microtissues
Javiera Jilberto, Samuel J. DePalma, Jason Lo +5
Engineered heart tissues (EHTs) present a potential solution to some of the current challenges in the treatment of heart disease; however, the development of mature, adult-like car…
Enhancing Mechanical Metamodels with a Generative Model-Based Augmented Training Dataset
Hiba Kobeissi, Saeed Mohammadzadeh, Emma Lejeune
Modeling biological soft tissue is complex in part due to material heterogeneity. Microstructural patterns, which play a major role in defining the mechanical behavior of these tis…