58 citations · 58 across the 3 of their papers we have counts for
3 papers
Balancing label resolution and computational cost in dynamical models of lipid metabolism
Paul Jonas Jost, Christoph Thiele, Jan Hasenauer
Lipid metabolism is a central biological process that is commonly studied using destructive mass-spectrometry experiments. A recently proposed strategy, uses multiple labels to ext…
PEtab-GUI: A graphical user interface to create, edit and inspect PEtab parameter estimation problems
Paul Jonas Jost, Frank T Bergmann, Daniel Weindl +1
Motivation: Parameter estimation is a cornerstone of data-driven modeling in systems biology. Yet, constructing such problems in a reproducible and accessible manner remains challe…
pyPESTO: A modular and scalable tool for parameter estimation for dynamic models
Yannik Schälte, Fabian Fröhlich, Paul J. Jost +14
Mechanistic models are important tools to describe and understand biological processes. However, they typically rely on unknown parameters, the estimation of which can be challengi…