3 papers
cs.LG2025
Departures: Distributional Transport for Single-Cell Perturbation Prediction with Neural Schrödinger Bridges
Changxi Chi, Yufei Huang, Jun Xia +4
Predicting single-cell perturbation outcomes directly advances gene function analysis and facilitates drug candidate selection, making it a key driver of both basic and translation…
cs.LG2025
PRESCRIBE: Predicting Single-Cell Responses with Bayesian Estimation
Jiabei Cheng, Changxi Chi, Jingbo Zhou +2
In single-cell perturbation prediction, a central task is to forecast the effects of perturbing a gene unseen in the training data. The efficacy of such predictions depends on two…
q-bio.QM2025
GRAPE: Heterogeneous Graph Representation Learning for Genetic Perturbation with Coding and Non-Coding Biotype
Changxi Chi, Jun Xia, Jingbo Zhou +3
Predicting genetic perturbations enables the identification of potentially crucial genes prior to wet-lab experiments, significantly improving overall experimental efficiency. Sinc…