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q-bio.GN2025
MergeDNA: Context-aware Genome Modeling with Dynamic Tokenization through Token Merging
Siyuan Li, Kai Yu, Anna Wang +7
Modeling genomic sequences faces two unsolved challenges: the information density varies widely across different regions, while there is no clearly defined minimum vocabulary unit.…
q-bio.GN2025
EnTao-GPM: DNA Foundation Model for Predicting the Germline Pathogenic Mutations
Zekai Lin, Haoran Sun, Yucheng Guo +8
Distinguishing pathogenic mutations from benign polymorphisms remains a critical challenge in precision medicine. EnTao-GPM, developed by Fudan University and BioMap, addresses thi…