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20242026
most citedArtificial Intelligence for Central Dogma-Centric Multi-Omics: Challenges and Breakthroughs

4 citations · 4 across the 7 of their papers we have counts for

collaborators

8 papers

cs.LG2026

OmniOpt: Taxonomy, Geometry, and Benchmarking of Modern Optimizers

Siyuan Li, Jiabao Pan, Yumou Liu +9

Optimizer selection for large-scale model training has become a system-level design decision constrained jointly by compute, memory, tuning budget, and task diversity, yet the land…

q-bio.GN2025

MergeDNA: Context-aware Genome Modeling with Dynamic Tokenization through Token Merging

Siyuan Li, Kai Yu, Anna Wang +7

Modeling genomic sequences faces two unsolved challenges: the information density varies widely across different regions, while there is no clearly defined minimum vocabulary unit.…

cs.CV2025

MergeMix: A Unified Augmentation Paradigm for Visual and Multi-Modal Understanding

Xin Jin, Siyuan Li, Siyong Jian +2

Vision-language alignment in multi-modal large language models (MLLMs) relies on supervised fine-tuning (SFT) or reinforcement learning (RL). To align multi-modal large language mo…

cs.LG2025

Rep-MTL: Unleashing the Power of Representation-level Task Saliency for Multi-Task Learning

Zedong Wang, Siyuan Li, Dan Xu

Despite the promise of Multi-Task Learning in leveraging complementary knowledge across tasks, existing multi-task optimization (MTO) techniques remain fixated on resolving conflic…

cs.LG2025

Taming LLMs by Scaling Learning Rates with Gradient Grouping

Siyuan Li, Juanxi Tian, Zedong Wang +4

Training large language models (LLMs) poses challenges due to their massive scale and heterogeneous architectures. While adaptive optimizers like AdamW help address gradient variat…

cs.CV2025

MergeVQ: A Unified Framework for Visual Generation and Representation with Disentangled Token Merging and Quantization

Siyuan Li, Luyuan Zhang, Zedong Wang +8

Masked Image Modeling (MIM) with Vector Quantization (VQ) has achieved great success in both self-supervised pre-training and image generation. However, most existing methods strug…

cs.LG2025

Life-Code: Central Dogma Modeling with Multi-Omics Sequence Unification

Zicheng Liu, Siyuan Li, Zhiyuan Chen +6

The interactions between DNA, RNA, and proteins are fundamental to biological processes, as illustrated by the central dogma of molecular biology. Although modern biological pre-tr…

q-bio.GN2024★ 4 cited

Artificial Intelligence for Central Dogma-Centric Multi-Omics: Challenges and Breakthroughs

Lei Xin, Caiyun Huang, Hao Li +8

With the rapid development of high-throughput sequencing platforms, an increasing number of omics technologies, such as genomics, metabolomics, and transcriptomics, are being appli…