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physics.bio-ph2025
Iterative improvement of free energy landscape reconstructions with optimal protocols derived from differentiable simulations
Oliver Cheng, Zosia Adamska, Michael P. Brenner +1
Free energy landscapes encode the kinetics, intermediates, and transition states that govern molecular processes and are thus a key target of single biomolecule research. Typical a…
physics.bio-ph2025
Combinatorial decision-making driven by multicomponent surface condensates
Aidan Zentner, Ethan V. Halingstad, Cameron Chalk +4
Living organisms rely on molecular networks, such as gene circuits and signaling pathways, for information processing and robust decision-making in crowded, noisy environments. Rec…