activity
20202026
most citedA meta-analysis of Boolean network models reveals design principles of gene regulatory networks

60 citations · 72 across the 5 of their papers we have counts for

collaborators

5 papers

q-bio.MN2026

Correcting hidden sampling biases in null models of canalizing Boolean networks

Ahana Ghosh, Claus Kadelka

Boolean networks are widely used to model gene regulatory systems. Their structural and dynamical properties are commonly interpreted by comparison with ensembles of random Boolean…

q-bio.MN2025

Canalization as a stabilizing principle of gene regulatory networks: a discrete dynamical systems perspective

Claus Kadelka

Gene regulatory networks exhibit remarkable stability, maintaining functional phenotypes despite genetic and environmental perturbations. Discrete dynamical models, such as Boolean…

q-bio.MN2024

Canalization reduces the nonlinearity of regulation in biological networks

Claus Kadelka, David Murrugarra

Biological networks such as gene regulatory networks possess desirable properties. They are more robust and controllable than random networks. This motivates the search for structu…

physics.soc-ph2022★ 12 cited

Projecting social contact matrices to populations stratified by binary attributes with known homophily

Claus Kadelka

Contact networks are heterogeneous. People with similar characteristics are more likely to interact, a phenomenon called assortative mixing or homophily. While age-assortativity is…

q-bio.MN2020★ 60 cited

A meta-analysis of Boolean network models reveals design principles of gene regulatory networks

Claus Kadelka, Taras-Michael Butrie, Evan Hilton +3

Gene regulatory networks (GRNs) play a central role in cellular decision-making. Understanding their structure and how it impacts their dynamics constitutes thus a fundamental biol…