activity
20242026
most citedDiffusion Models at the Drug Discovery Frontier: A Review on Generating Small Molecules versus Therapeutic Peptides

9 citations · 12 across the 8 of their papers we have counts for

collaborators

9 papers

q-bio.BM2026

Piecewise integrability of the discrete Hasimoto map for analytic prediction and design of helical peptides

Yiquan Wang

The representation of protein backbone geometry through the discrete nonlinear Schrödinger equation provides a theoretical connection between biological structure and integrable sy…

q-bio.BM2026

Spectral analysis of protein backbone geometry reveals abrupt helix--coil boundaries

Yiquan Wang

The boundaries of cooperative helix--coil transitions influence protein allostery and conformational dynamics, yet the persistent one-to-two-residue ambiguity in their assignment r…

q-bio.BM2026★ 1 cited

Descriptive power and predictive limits of a discrete Hasimoto--DNLS model of protein backbone structure

Yiquan Wang

Determining 3D protein structure from sequence remains a fundamental biophysical challenge. The C backbone's discrete Frenet geometry maps, via a Hasimoto transform, to a compl…

cs.LG2025★ 9 cited

Diffusion Models at the Drug Discovery Frontier: A Review on Generating Small Molecules versus Therapeutic Peptides

Yiquan Wang, Yahui Ma, Yuhan Chang +4

Diffusion models have emerged as a leading framework in generative modeling, poised to transform the traditionally slow and costly process of drug discovery. This review provides a…

cs.AI2025

AI Driven Discovery of Bio Ecological Mediation in Cascading Heatwave Risks

Yiquan Wang, Tin-Yeh Huang, Qingyun Gao +2

Compound heatwaves increasingly trigger complex cascading failures that propagate through interconnected physical and human systems, yet the fragmentation of disciplinary knowledge…

cs.CL2025

Construction and educational application of a linguistically grounded dependency treebank for Uyghur

Jiaxin Zuo, Yiquan Wang, Yuan Pan +1

Developing effective educational technologies for low-resource agglutinative languages like Uyghur is often hindered by the mismatch between existing annotation frameworks and spec…

cs.LG2025★ 1 cited

STGCN-LSTM for Olympic Medal Prediction: Dynamic Power Modeling and Causal Policy Optimization

Yiquan Wang, Jiaying Wang, Tin-Yeh Huang +2

This paper proposes a novel hybrid model, STGCN-LSTM, to forecast Olympic medal distributions by integrating the spatio-temporal relationships among countries and the long-term dep…

cs.SI2024★ 1 cited

A Personalized MOOC Learning Group and Course Recommendation Method Based on Graph Neural Network and Social Network Analysis

Zijin Luo, Xu Wang, Yiquan Wang +2

In order to enhance students' initiative and participation in MOOC learning, this study constructed a multi-level network model based on Social Network Analysis (SNA). The model ma…

cs.NE2024

Octopus Inspired Optimization (OIO): A Hierarchical Framework for Navigating Protein Fitness Landscapes

Xu Wang, Yiquan Wang, Tin-Yeh Huang +5

Navigating vast, rugged biological fitness landscapes to discover high-value functional patterns-such as optimal protein sequences-is a central challenge in health informatics. How…