2 papers
q-bio.BM2009
Adaptation through stochastic switching into transient mutators in finite asexual populations
Muyoung Heo, Louis Kang, Eugene Shakhnovich
The importance of mutator clones in the adaptive evolution of asexual populations is not fully understood. Here we address this problem by using an ab initio microscopic model of l…
q-bio.PE2008★ 22 cited
Emergence of species in evolutionary simulated annealing
Muyoung Heo, Louis Kang, Eugene I. Shakhnovich
Which factors govern the evolution of mutation rates and emergence of species? Here, we address this question using a first principles model of life where population dynamics of as…