38 citations · 59 across the 9 of their papers we have counts for
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Liquid-liquid phase separation precedes crystallization in supercooled water-glycerol solutions
Iason Andronis, Sharon Berkowicz, Mariia Filianina +10
Understanding the structural evolution of supercooled water-glycerol solutions is important for cryopreservation, yet distinguishing liquid-state transformations from ice crystalli…
X-ray photon correlation spectroscopy of hydrated lysozyme at elevated pressures
Milla Åhlfeldt, Maddalena Bin, Anita Girelli +12
Pressure provides a powerful parameter to control the protein conformation state, which at sufficiently high values can lead to unfolding. Here, we investigate the effects of incre…
Nanoscale Protein Diffusion in Supercooled Cryoprotectant Solutions
Maddalena Bin, Anita Girelli, Mariia Filianina +15
Vitrification during cryopreservation requires a quantitative understanding of protein transport in deeply supercooled cryoprotectant solutions, yet direct measurements at molecula…
Depletion-Induced Interactions Modulate Nanoscale Protein Diffusion in Polymeric Crowder Solutions
Michelle Dargasz, Nimmi Das Anthuparambil, Sebastian Retzbach +26
Macromolecular crowding plays a crucial role in modulating protein dynamics in cellular and in vitro environments. Polymeric crowders such as dextran and Ficoll are known to induce…
Softness and Hydrodynamic Interactions Regulate Lipoprotein Transport in Crowded Yolk Environments
Nimmi Das Anthuparambil, Michelle Dargasz, Sonja Timmermann +27
Low-density lipoproteins (LDLs) serve as nutrient reservoirs in egg yolk for embryonic development and as promising drug carriers. Both roles critically depend on their mobility in…
Supercritical density fluctuations and structural heterogeneity in supercooled water-glycerol microdroplets
Sharon Berkowicz, Iason Andronis, Anita Girelli +9
Recent experiments and theoretical studies strongly indicate that water exhibits a liquid-liquid phase transition (LLPT) in the supercooled domain. An open question is how the LLPT…
Coherent X-rays reveal anomalous molecular diffusion and cage effects in crowded protein solutions
Anita Girelli, Maddalena Bin, Mariia Filianina +38
Understanding protein motion within the cell is crucial for predicting reaction rates and macromolecular transport in the cytoplasm. A key question is how crowded environments affe…
Nanocrystallites Modulate Intermolecular Interactions in Cryoprotected Protein Solutions
Mariia Filianina, Maddalena Bin, Sharon Berkowicz +7
Studying protein interactions at low temperatures has important implications for optimizing cryostorage processes of biological tissue, food, and protein-based drugs. One of the ma…
Coherent X-ray Scattering Reveals Nanoscale Fluctuations in Hydrated Proteins
Maddalena Bin, Mario Reiser, Mariia Filianina +15
Hydrated proteins undergo a transition in the deeply supercooled regime, which is attributed to rapid changes in hydration water and protein structural dynamics. Here, we investiga…