3 papers · 1 filter
Sensitivity-driven Personalization of a Glucoregulatory Model for Digital Twin Therapeutics in Type 1 Diabetes
Clara Escorihuela-Altaba, Vihangkumar V. Naik, Eleonora Manzoni +1
Digital twins are increasingly used in diabetes research, but reproducing individual glucose dynamics requires accurate identification of glucoregulatory model parameters. Traditio…
Joint State-Parameter Inference Enhances Estimation Performance in Model-Based Digital Therapeutics for Type 1 Diabetes
Milad Banitalebi Dehkordi, Vihangkumar V. Naik, Manas Mejari +2
Blood glucose estimation is the cornerstone of model-based decision support (DS) and Automated Insulin Delivery (AID) systems. Control systems that rely on physiologic/compartmenta…
Advanced Hybrid Automated Insulin Delivery System based on Successive Linearization Model Predictive Control: The UniBE System
Vihangkumar V. Naik, Eleonora Manzoni, Clara Escorihuela-Altaba +1
Background and objective: Hybrid automated insulin delivery (hAID) systems represent the most advanced therapy for type 1 diabetes (T1D). Current systems rely on linear or lineariz…