2 papers
q-bio.GN2025
ImmunoNX: a robust bioinformatics workflow to support personalized neoantigen vaccine trials
Kartik Singhal, Evelyn Schmidt, Susanna Kiwala +36
Personalized neoantigen vaccines represent a promising immunotherapy approach that harnesses tumor-specific antigens to stimulate anti-tumor immune responses. However, the design o…
q-bio.GN2024
Evaluation of simulation methods for tumor subclonal reconstruction
Jiaying Lai, Yunzhou Liu, Robert B. Scharpf +1
Most neoplastic tumors originate from a single cell, and their evolution can be genetically traced through lineages characterized by common alterations such as small somatic mutati…