3 papers
stat.ME2025
Prenatal alcohol exposure and child cognition: semi-continuous exposures, causal inference and evidence synthesis
Xiaoya Wang, Richard J. Cook, Yeying Zhu +5
We address the challenge of causal inference status and the dose-response effects with a semi-continuous exposure. A two-stage approach is proposed using estimating equation for mu…
stat.ME2025
Two-stage Estimation for Causal Inference Involving a Semi-continuous Exposure
Xiaoya Wang, Richard J. Cook, Yeying Zhu +5
Methods for causal inference are well developed for binary and continuous exposures, but in many settings, the exposure has a substantial mass at zero-such exposures are called sem…
stat.ME2023
Semi-parametric Benchmark Dose Analysis with Monotone Additive Models
Alex Stringer, Tugba Akkaya Hocagil, Richard Cook +3
Benchmark dose analysis aims to estimate the level of exposure to a toxin that results in a clinically-significant adverse outcome and quantifies uncertainty using the lower limit…