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stat.ME2025
Causal Inference and Evidence Synthesis for Semi-continuous Exposures with Multiple Outcomes
Xiaoya Wang, Richard J. Cook, Yeying Zhu +6
Semi-continuous exposure variables, featuring a point mass at zero and a continuous dose in exposed individuals, arise frequently in epidemiology. In such settings, investigators m…
stat.ME2025
Two-stage Estimation for Causal Inference Involving a Semi-continuous Exposure
Xiaoya Wang, Richard J. Cook, Yeying Zhu +5
Methods for causal inference are well developed for binary and continuous exposures, but in many settings, the exposure has a substantial mass at zero-such exposures are called sem…
stat.ME2023
Semi-parametric Benchmark Dose Analysis with Monotone Additive Models
Alex Stringer, Tugba Akkaya Hocagil, Richard Cook +3
Benchmark dose analysis aims to estimate the level of exposure to a toxin that results in a clinically-significant adverse outcome and quantifies uncertainty using the lower limit…