8 citations · 10 across the 13 of their papers we have counts for
17 papers
Sparse cubical complexes for efficient topology-preservation in image data
Alexander H. Berger, Marco Fontana, Daniel Rueckert +3
Persistent homology (PH) is a frequently used tool for extracting and preserving topological information from image data, particularly in image segmentation, where preservation of…
Memorisation bias in medical AI
Moritz A. Knolle, Martin J. Menten, Laurin Lux +5
Medical AI models hold immense potential to improve patient outcomes, but they are also known to unintentionally memorise individual records from their training datasets. While suc…
Temporally Consistent Graph Extraction and Matching for Longitudinal Angiographic Images
Linus Kreitner, Laurin Lux, Carmen Baumann +2
Recent advances in angiographic imaging have enabled longitudinal visualization of the microvasculature. Image processing pipelines based on vessel graphs are able to resolve subtl…
It depends: Incorporating correlations for joint aleatoric and epistemic uncertainties of high-dimensional output spaces
Leonhard F. Feiner, Manuel Nickel, Martin Menten +6
Uncertainty Quantification (UQ) plays a vital role in enhancing the reliability of deep learning model predictions, especially in scenarios with high-dimensional output spaces. Thi…
Beyond scalar losses: calibrating segmentation models via gradient vector field surgery
Laurin Lux, Alexander H. Berger, Moritz Knolle +2
Region-based loss functions, such as the Dice loss, have established themselves as the de facto standard for highly class- and region-imbalanced segmentation tasks. However, models…
Synthetic Vasculature and Pathology Enhance Vision-Language Model Reasoning
Chenjun Li, Cheng Wan, Laurin Lux +4
Vision-Language Models (VLMs) offer a promising path toward interpretable medical diagnosis by allowing users to ask about clinical explanations alongside predictions and across di…
Addressing Annotation Scarcity in Hyperspectral Brain Image Segmentation with Unsupervised Domain Adaptation
Tim Mach, Daniel Rueckert, Alex Berger +2
This work presents a novel deep learning framework for segmenting cerebral vasculature in hyperspectral brain images. We address the critical challenge of severe label scarcity, wh…
A Graph-Based Framework for Interpretable Whole Slide Image Analysis
Alexander Weers, Alexander H. Berger, Laurin Lux +3
The histopathological analysis of whole-slide images (WSIs) is fundamental to cancer diagnosis but is a time-consuming and expert-driven process. While deep learning methods show p…
Fine-tuning Vision Language Models with Graph-based Knowledge for Explainable Medical Image Analysis
Chenjun Li, Laurin Lux, Alexander H. Berger +3
Accurate staging of Diabetic Retinopathy (DR) is essential for guiding timely interventions and preventing vision loss. However, current staging models are hardly interpretable, an…
Redefining spectral unmixing for in-vivo brain tissue analysis from hyperspectral imaging
Martin Hartenberger, Huzeyfe Ayaz, Fatih Ozlugedik +12
In this paper, we propose a methodology for extracting molecular tumor biomarkers from hyperspectral imaging (HSI), an emerging technology for intraoperative tissue assessment. To…
Interpretable Retinal Disease Prediction Using Biology-Informed Heterogeneous Graph Representations
Laurin Lux, Alexander H. Berger, Maria Romeo Tricas +8
Interpretability is crucial for utilizing machine learning models as clinical decision support tools for medical diagnostics. However, most state-of-the-art image classifiers based…
Pitfalls of topology-aware image segmentation
Alexander H. Berger, Laurin Lux, Alexander Weers +3
Topological correctness, i.e., the preservation of structural integrity and specific characteristics of shape, is a fundamental requirement for medical imaging tasks, such as neuro…
A Lightweight Optimization Framework for Estimating 3D Brain Tumor Infiltration
Jonas Weidner, Michal Balcerak, Ivan Ezhov +6
Glioblastoma, the most aggressive primary brain tumor, poses a severe clinical challenge due to its diffuse microscopic infiltration, which remains largely undetected on standard M…
Topograph: An efficient Graph-Based Framework for Strictly Topology Preserving Image Segmentation
Laurin Lux, Alexander H. Berger, Alexander Weers +4
Topological correctness plays a critical role in many image segmentation tasks, yet most networks are trained using pixel-wise loss functions, such as Dice, neglecting topological…
Topologically Faithful Multi-class Segmentation in Medical Images
Alexander H. Berger, Nico Stucki, Laurin Lux +6
Topological accuracy in medical image segmentation is a highly important property for downstream applications such as network analysis and flow modeling in vessels or cell counting…
Cross-domain and Cross-dimension Learning for Image-to-Graph Transformers
Alexander H. Berger, Laurin Lux, Suprosanna Shit +5
Direct image-to-graph transformation is a challenging task that involves solving object detection and relationship prediction in a single model. Due to this task's complexity, larg…
A Learnable Prior Improves Inverse Tumor Growth Modeling
Jonas Weidner, Ivan Ezhov, Michal Balcerak +11
Biophysical modeling, particularly involving partial differential equations (PDEs), offers significant potential for tailoring disease treatment protocols to individual patients. H…