Mechanisms of thrombin inhibition by protein S and the TFPIα-fVshort-protein S complex

Alexander G. Ginsberg, Josefin Ahnström, James T. B. Crawley +5

Protein S (PS) is a notable anticoagulant implicated in both bleeding and thrombotic disorders, making it a promising drug target. Importantly, PS enhances the anticoagulant functi…