14 papers
Multiscale retinal flow on a spherical cap of varying aperture
Chang Lin, Zilong Song, Bob Eisenberg +2
Modelling retinal haemodynamics is crucial for understanding retinal microcirculation but is computationally demanding because it involves coupling between the vasculature and surr…
Interpretable Fundus Image Classification via Ring-Based Retinal Vasculature Features
Xiaoyan Li, Shixin Xu, Arvind Gupta +1
Retinal fundus photography is widely used for screening and monitoring ocular diseases, but many modern classification pipelines rely on deep latent representations and provide lim…
AQP4 Regulates Gap-Dominated Glymphatic Clearance through Dynamic Gliovascular Coupling
Tanran Zhang, Huaxiong Huang, Robert Eisenberg +1
Aquaporin-4 (AQP4) is enriched at perivascular astrocytic endfeet, and impaired AQP4 function or localization is associated with reduced glymphatic transport. However, mechanical m…
TWLR: Text-Guided Weakly-Supervised Lesion Localization and Severity Regression for Explainable Diabetic Retinopathy Grading
Xi Luo, Shixin Xu, Ying Xie +4
Accurate medical image analysis can greatly assist clinical diagnosis, but its effectiveness relies on high-quality expert annotations Obtaining pixel-level labels for medical imag…
A novel multiscale modelling for the hemodynamics in retinal microcirculation with an analytic solution for the capillary-tissue coupled system
Chang Lin, Zilong Song, Robert Eisenberg +2
Mathematical modelling of the microcirculatory hemodynamics in the retina is an essential tool for understanding various diseases of the retina, yet remains challenging due to the…
Glymphatic Clearance in the Optic Nerve: A Multidomain Electro-osmostic Model
Shanfeng Xiao, Huaxiong Huang, Robert Eisenberg +2
Effective metabolic waste clearance and maintaining ionic homeostasis are essential for the health and normal function of the central nervous system. To understand its mechanism an…