4 papers
Pinned Boundaries Delay Contraction and Shape Stress Relaxation in Active Gels
Aniket Marne, James Clarke, Aravind Rao +6
Cells dynamically generate, transmit, and dissipate stress. Central to these processes is the actomyosin cortex, an active contractile material that drives cellular mechanical beha…
Experimental methods to control pinned and coupled actomyosin contraction events
James Clarke, Hyunjae Lee, Kyla Wong +4
Actin and myosin drive many instances of force generation, deformation, and shape change in cells, tissues, and organisms. In particular, cytoskeletal actomyosin is remarkable in i…
Nonlinear contractile response of actomyosin active gels to control signals
James Clarke, Francis Cavanna, Aniket Marne +2
Biological systems tightly regulate their physiological state using control signals. This includes the actomyosin cytoskeleton, a contractile active gel that consumes chemical free…
Morphological Control of Bundled Actin Networks Subject to Fixed-Mass Depletion
James Clarke, Lauren Melcher, Anne D. Crowell +10
Depletion interactions are thought to significantly contribute to the organization of intracellular structures in the crowded cytosol. The strength of depletion interactions depend…