4 papers
On Growth and Form, and Function: Reusable Regulatory Handles Control Phenotypic Variation
Benedikt Hartl, Milton L. Montero, Marcello Barylli +2
How phenotypic transformations are implemented by changes in underlying regulatory dynamics remains a central question in developmental biology. Inspired by D'Arcy Thompson's 1917…
Self-Organising Digital Circuits
Marcello Barylli, Gabriel Béna, Alexander Mordvintsev +2
Fault tolerance in classical computing has traditionally relied on static strategies like hardware redundancy and error-correcting codes. Biological systems, in contrast, exhibit a…
Hypernetworks That Evolve Themselves
Joachim Winther Pedersen, Erwan Plantec, Eleni Nisioti +4
How can neural networks evolve themselves without relying on external optimizers? We propose Self-Referential Graph HyperNetworks, systems where the very machinery of variation and…
Biological Multi-Layer and Single Cell Network-Based Multiomics Models - a Review
Marcello Barylli, Joyaditya Saha, Tineke E. Buffart +4
Recent advances in single cell sequencing and multi-omics techniques have significantly improved our understanding of biological phenomena and our capacity to model them. Despite c…