1 citations · 1 across the 5 of their papers we have counts for
11 papers
Patterns in Individual Blood Count Trajectories in the UK Biobank Characterise Disease-Specific Signatures and Anticipate Pan-Cancer Risk
Riya Nagar, Abicumaran Uthamacumaran, Adelaide de Vecchi +1
We investigate the longitudinal behaviour of blood markers from common haematological tests as a marker of disease and as a function of disease progression in a variety of conditio…
Systematic Reconstruction of Disease Networks from Longitudinal Blood Data for Causal Discovery and Intervention Analysis
David Patrick Duys Montealegre, Alexander Fulton, Mahta Haghighat Ghahfarokhi +2
We explore the hyperparameters and introduce a methodological framework to convert disease patterns from time series data of blood test results into correlation graphs for causal h…
XGBoost-Powered Digital Twins Leverage Routine Blood Tests for Early Detection of Cancer and Cardiovascular Disease
Lo Kai Shun John, Riya Nagar, Abicumaran Uthamacumaran +1
Early detection of cancer and cardiovascular diseases is fundamental to improving patient outcomes and reducing healthcare expenditure. Current cancer screening programs are target…
Exhaustive Investigation of CBC-Derived Biomarker Ratios for Clinical Outcome Prediction: The RDW-to-MCHC Ratio as a Novel Mortality Predictor in Critical Care
Dmytro Leontiev, Abicumaran Uthamacumaran, Riya Nagar +1
Ratios of common biomarkers and blood analytes are well established for early detection and predictive purposes. Early risk stratification in critical care is often limited by the…
Multi-omic Enriched Blood-Derived Digital Signatures Reveal Mechanistic and Confounding Disease Clusters for Differential Diagnosis
Bolin Liu, Abicumaran Uthamacumaran, Alexander Fulton +1
Understanding disease relationships through blood biomarkers offers a pathway toward data-driven taxonomy and precision medicine. In this study, we constructed a digital blood twin…
Similarity Analysis of Blood Count Reference Intervals Across Continents Reveals No Reproducible Population or Geography-Linked Structure and Supports Personalised Values
Kunlin Wu, Abicumaran Uthamacumaran, Hector Zenil
Blood reference intervals (RIs) underpin diagnostic interpretation and therapeutic monitoring worldwide. However, many widely used RI systems originate from limited historical coho…