5 papers
Universal Quartic Scaling Law for Kerr-Type Interactions: Projection-Law Factorization Across Nonlinear Quantum Platforms
Xiaochen Liu, Ken-Tye Yong
We present a rigorous derivation and numerical validation of a universal projection-law factorization for quartic nonlinear coupling rates across physically distinct platforms. The…
Generative Modeling in Protein Design: Neural Representations, Conditional Generation, and Evaluation Standards
Senura Hansaja Wanasekara, Minh-Duong Nguyen, Xiaochen Liu +2
Generative modeling has become a central paradigm in protein research, extending machine learning beyond structure prediction toward sequence design, backbone generation, inverse f…
Molecular Dynamics Simulations Reveal PolyQ-Length-Dependent Conformational Changes in Huntingtin Exon-1: Implications for Environmental Co-Solvent Modulation of Aggregation-Prone States
Jai Geddes-Nelson, Xiaochen Liu, Ken-Tye Yong
Huntington's disease (HD) is caused by CAG-repeat expansion in HTT, which lengthens the polyglutamine (polyQ) tract in huntingtin (HTT) and promotes misfolding and aggregation. Whi…
Unified Effective Field Theory for Nonlinear and Quantum Optics
Xiaochen Liu, Ken-Tye Yong
Predicting phenomena that mix few-photon quantum optics with strong field nonlinear optics is hindered by the use of separate theoretical formalisms for each regime. We close this…
FOSS solution for Molecular Dynamics Simulation Automation and Collaboration with MDSGAT
Jai Geddes Nelson, Xiaochen Liu, Ken Tye Yong
The process of setting up and successfully running Molecular Dynamics Simulations (MDS) is outlined to be incredibly labour and computationally expensive with a very high barrier t…