activity
20212026
most citedThe TopCoW Challenge -- Topology-Aware Circle of Willis Segmentation for CT and MR Angiography

14 citations · 33 across the 36 of their papers we have counts for

collaborators

38 papers

cs.LG2026

Memorisation bias in medical AI

Moritz A. Knolle, Martin J. Menten, Laurin Lux +5

Medical AI models hold immense potential to improve patient outcomes, but they are also known to unintentionally memorise individual records from their training datasets. While suc…

cs.CV2026

Temporally Consistent Graph Extraction and Matching for Longitudinal Angiographic Images

Linus Kreitner, Laurin Lux, Carmen Baumann +2

Recent advances in angiographic imaging have enabled longitudinal visualization of the microvasculature. Image processing pipelines based on vessel graphs are able to resolve subtl…

cs.LG2026

It depends: Incorporating correlations for joint aleatoric and epistemic uncertainties of high-dimensional output spaces

Leonhard F. Feiner, Manuel Nickel, Martin Menten +6

Uncertainty Quantification (UQ) plays a vital role in enhancing the reliability of deep learning model predictions, especially in scenarios with high-dimensional output spaces. Thi…

cs.CV2026

When the Edit Changes the Patient: Measuring Identity Preservation in Counterfactual Retinal Images

Andrea Posada, Wenke Karbole, Bach Ngoc Doan +9

Counterfactual medical image generation aims to modify an existing image to reflect a hypothetical scenario in which certain characteristics of the imaged subject are altered, whil…

cs.CL2026

Weighting What Matters: Boosting Sample Efficiency in Medical Report Generation via Token Reweighting

Alexander Weers, Daniel Rueckert, Martin J. Menten

Training vision-language models (VLMs) for medical report generation is often hindered by the scarcity of high-quality annotated data. This work evaluates the use of a weighted los…

cs.LG2026

Step-resolved data attribution for looped transformers

Georgios Kaissis, David Mildenberger, Juan Felipe Gomez +2

We study how individual training examples shape the internal computation of looped transformers, where a shared block is applied for recurrent iterations to enable latent reaso…

cs.LG2025

Stochastic Siamese MAE Pretraining for Longitudinal Medical Images

Taha Emre, Arunava Chakravarty, Thomas Pinetz +9

Temporally aware image representations are crucial for capturing disease progression in 3D volumes of longitudinal medical datasets. However, recent state-of-the-art self-supervise…

cs.CV2025

Synthetic Vasculature and Pathology Enhance Vision-Language Model Reasoning

Chenjun Li, Cheng Wan, Laurin Lux +4

Vision-Language Models (VLMs) offer a promising path toward interpretable medical diagnosis by allowing users to ask about clinical explanations alongside predictions and across di…

cs.LG2025

Efficient numeracy in language models through single-token number embeddings

Linus Kreitner, Paul Hager, Jonathan Mengedoht +3

To drive progress in science and engineering, large language models (LLMs) must be able to process large amounts of numerical data and solve long calculations efficiently. This is…

cs.LG2025

On Arbitrary Predictions from Equally Valid Models

Sarah Lockfisch, Kristian Schwethelm, Martin Menten +4

Model multiplicity refers to the existence of multiple machine learning models that describe the data equally well but may produce different predictions on individual samples. In m…

cs.LG2025

A Tale of Two Classes: Adapting Supervised Contrastive Learning to Binary Imbalanced Datasets

David Mildenberger, Paul Hager, Daniel Rueckert +1

Supervised contrastive learning (SupCon) has proven to be a powerful alternative to the standard cross-entropy loss for classification of multi-class balanced datasets. However, it…

eess.IV2025

Skelite: Compact Neural Networks for Efficient Iterative Skeletonization

Luis D. Reyes Vargas, Martin J. Menten, Johannes C. Paetzold +2

Skeletonization extracts thin representations from images that compactly encode their geometry and topology. These representations have become an important topological prior for pr…

cs.CV2025

Fine-tuning Vision Language Models with Graph-based Knowledge for Explainable Medical Image Analysis

Chenjun Li, Laurin Lux, Alexander H. Berger +3

Accurate staging of Diabetic Retinopathy (DR) is essential for guiding timely interventions and preventing vision loss. However, current staging models are hardly interpretable, an…

physics.med-ph2025

Redefining spectral unmixing for in-vivo brain tissue analysis from hyperspectral imaging

Martin Hartenberger, Huzeyfe Ayaz, Fatih Ozlugedik +12

In this paper, we propose a methodology for extracting molecular tumor biomarkers from hyperspectral imaging (HSI), an emerging technology for intraoperative tissue assessment. To…

cs.CV2025

Interpretable Retinal Disease Prediction Using Biology-Informed Heterogeneous Graph Representations

Laurin Lux, Alexander H. Berger, Maria Romeo Tricas +8

Interpretability is crucial for utilizing machine learning models as clinical decision support tools for medical diagnostics. However, most state-of-the-art image classifiers based…

cs.CV2024★ 1 cited

Pitfalls of topology-aware image segmentation

Alexander H. Berger, Laurin Lux, Alexander Weers +3

Topological correctness, i.e., the preservation of structural integrity and specific characteristics of shape, is a fundamental requirement for medical imaging tasks, such as neuro…

cs.CV2024

Interpretable deformable image registration: A geometric deep learning perspective

Vasiliki Sideri-Lampretsa, Nil Stolt-Ansó, Huaqi Qiu +4

Deformable image registration poses a challenging problem where, unlike most deep learning tasks, a complex relationship between multiple coordinate systems has to be considered. A…

cs.LG2024★ 1 cited

OTIS: Learning High-Quality Time Series Features With Tiny Encoders

Özgün Turgut, Philip Müller, Martin J. Menten +1

We introduce OTIS, an open time series encoder that yields high-quality time series features for downstream deployment on any system, including resource-constrained wearables and i…

cs.AI2024

Specialized curricula for training vision-language models in retinal image analysis

Robbie Holland, Thomas R. P. Taylor, Christopher Holmes +13

Clinicians spend a significant amount of time reviewing medical images and transcribing their findings regarding patient diagnosis, referral and treatment in text form. Vision-lang…

eess.IV2024

Deep-learning-based clustering of OCT images for biomarker discovery in age-related macular degeneration (Pinnacle study report 4)

Robbie Holland, Rebecca Kaye, Ahmed M. Hagag +9

Diseases are currently managed by grading systems, where patients are stratified by grading systems into stages that indicate patient risk and guide clinical management. However, t…

eess.IV2024

Diff-Def: Diffusion-Generated Deformation Fields for Conditional Atlases

Sophie Starck, Vasiliki Sideri-Lampretsa, Bernhard Kainz +3

Anatomical atlases are widely used for population studies and analysis. Conditional atlases target a specific sub-population defined via certain conditions, such as demographics or…

cs.CV2024

Spatiotemporal Representation Learning for Short and Long Medical Image Time Series

Chengzhi Shen, Martin J. Menten, Hrvoje Bogunović +7

Analyzing temporal developments is crucial for the accurate prognosis of many medical conditions. Temporal changes that occur over short time scales are key to assessing the health…

cs.CV2024

Cross-domain and Cross-dimension Learning for Image-to-Graph Transformers

Alexander H. Berger, Laurin Lux, Suprosanna Shit +5

Direct image-to-graph transformation is a challenging task that involves solving object detection and relationship prediction in a single model. Due to this task's complexity, larg…

cs.CV2023★ 14 cited

The TopCoW Challenge -- Topology-Aware Circle of Willis Segmentation for CT and MR Angiography

Kaiyuan Yang, Fabio Musio, Yihui Ma +112

The Circle of Willis (CoW) is an important network of arteries connecting major circulations of the brain. Its vascular architecture is believed to influence the risk, severity, an…