4 papers
Mid-wave infrared photothermal microscopy for molecular and metabolic imaging in deep tissues and spheroids
Mingsheng Li, Yuhao Yuan, Guangrui Ding +11
High-resolution chemical imaging within deep tissues and intact spheroids remains a grand challenge. Here, we introduce mid-wave infrared photothermal (MWIP) microscopy operating i…
Mid-Infrared Photothermal Relaxation Intensity Diffraction Tomography for Video-rate Volumetric Chemical Imaging
Danchen Jia, Dashan Dong, Tongyu Li +5
Three-dimensional molecular imaging of living cells is essential for unraveling cellular metabolism and response to therapies. However, existing volumetric methods, including fluor…
Transfer-Function Approach to Substrate-Enhanced Diffraction Tomography
Tongyu Li, Yi Shen, Dashan Dong +4
Forward and backward scattering provide complementary volumetric and interfacial information, yet conventional three-dimensional (3D) imaging typically accesses only one. In this L…
Mid-infrared Energy Deposition Spectroscopy
Jiaze Yin, Christian Pfluegl, Chu C. Teng +6
Photothermal microscopy is an emerging tool for measuring light-matter interactions with single-molecule sensitivity. It is generally believed that the spectral acquisition speed i…