most citedSpeckle suppression in digital in-line holographic microscopy through liquid crystal dynamic scattering

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physics.optics2026

Hybrid spectral-spatial domain registration for nanometric tracking in digital in-line holographic microscopy

Kamil Kalinowski, Mikolaj Rogalski, Piotr Arcab +3

Digital in-line holographic microscopy enables label-free tracking and metrology, but achieving nanometric sub-pixel displacement accuracy over a wide capture range remains challen…

physics.optics2026

YOSO: single-frame Gerchberg-Saxton phase retrieval with AI-based data augmentation for in-line holography

Julianna Winnik, Adam Walocha, Wojciech Ogonowski +9

We present YOSO (You Only Shot Once), a single-frame phase retrieval framework for digital in-line holographic microscopy (DIHM) in which supervised deep learning is used to numeri…

physics.optics2026

High-Fidelity Single-Shot Quantitative Differential Phase Microscopy Using Pseudothermal Sagnac Interferometer

Pawel Goclowski, Hong Mao, Maciek Trusiak +2

In this letter, a high-fidelity single-shot differential quantitative phase microscopy (dQPM) method is presented to effectively image nearly transparent biological samples. The pr…

physics.optics2026

Near-infrared lensless holographic microscopy on a visible sensor enables label-free high-throughput imaging in strong scattering

Emilia Wdowiak, Piotr Arcab, Mikolaj Rogalski +6

Lensless digital holographic microscopy (LDHM) relies on interference between an unscattered reference wave and a weakly scattered object wave - an assumption that rapidly fails in…

physics.optics2026★ 2 cited

The mixture of glycerin with tartrazine: a solution to reversibly increase tissue transparency for in vitro quantitative phase imaging

Mikolaj Krysa, Anna Chwastowicz, Malgorzata Lenarcik +3

Thick tissue sections strongly scatter and absorb light, which limits transmission-based label-free examination via quantitative phase imaging (QPI) modalities. Here we introduce a…

physics.optics2026

Lateral shearing optical diffraction tomography of brain organoid with reduced spatial coherence

Pawel Goclowski, Julianna Winnik, Vishesh Dubey +6

Optical diffraction tomography (ODT) is a powerful technique for quantitative, label-free reconstruction of the three-dimensional refractive index (RI) distribution of biological s…

physics.optics2025

Low-dose Chemically Specific Bioimaging via Deep-UV Lensless Holographic Microscopy on a Standard Camera

Piotr Arcab, Mikolaj Rogalski, Karolina Niedziela +11

Deep-ultraviolet (DUV) microscopy can provide label-free biochemical contrast by exploiting the intrinsic absorption of nucleic acids, proteins and lipids, offering chemically spec…

physics.optics2025

Bayesian inference for precise and uncertainty-quantified single-shot widefield interferometric geometrical nanometrology

Damian Suski, Maria Cywinska, Julianna Winnik +5

Advanced geometrical nanometrology is critical for process control in semiconductor manufacturing, supporting applications in, e.g., photonic integrated circuits, nanoelectronics,…

physics.optics2025

OSI-flex: Optimization-Based Shearing Interferometry for Joint Phase and Shear Estimation Using a Flexible Open-Source Framework

Julianna Winnik, Damian Suski, Matyáš Heto +4

Shearing interferometry is a common-path quantitative phase imaging technique in which an object beam interferes with a laterally shifted replica of itself, providing high temporal…

physics.optics2025★ 2 cited

Speckle suppression in digital in-line holographic microscopy through liquid crystal dynamic scattering

Emilia Wdowiak, Nathan Spiller, Tianxin Wang +7

We demonstrate speckle noise reduction in an in-line holographic imaging system using a Zwitterion-doped liquid crystal dynamic scatterer (LCDS) cell diffuser. Integrated into a mi…

physics.optics2025

Gigavoxel-Scale Multiple-Scattering-Aware Lensless Holotomography

Mikolaj Rogalski, Julianna Winnik, Julia Dudek +6

Holotomography (HT) has revolutionized quantitative label-free 3D imaging, yet conventional lens-based implementations are fundamentally constrained in field-of-view (FOV) and imag…