4 papers
Propelling catalytic structures using active phase separation
Benjamin Sorkin, Ned S. Wingreen
Living systems routinely consume energy to achieve motility, often using intricate biomolecular machinery. In this work, we show that active droplets can sustain indefinite self-pr…
Polymer-Residue Accessibility Shapes Sequence Dependence of Critical Temperatures for Phase Separation
J. Pedro de Souza, Benjamin Sorkin, Amala Akkiraju +2
Biological polymers, such as intrinsically disordered proteins, play a central role in cellular biology, including mediating phase separation and controlling activity of biological…
Consistent thermodynamics reconstructed from transitions between nonequilibrium steady-states
Rémi Goerlich, Benjamin Sorkin, Dima Boriskovsky +4
Constructing a thermodynamic framework for nonequilibrium systems remains a major challenge, as quantities such as temperature and free energy often become ambiguous when inferred…
Accelerated Ostwald ripening by chemical activity
Benjamin Sorkin, Ned S. Wingreen
Phase separation of biomolecular condensates promotes membrane-free compartmentalization in cells. The dynamics of these biocondensates is routinely regulated by energy-consuming p…