4 papers
Roadmap for Condensates in Cell Biology
Dilimulati Aierken, Sebastian Aland, Stefano Bo +38
Biomolecular condensates govern essential cellular processes yet elude description by traditional equilibrium models. This roadmap, distilled from structured discussions at a works…
Harvesting chemical power from cyclic environments
Pranay Jaiswal, Ivar S. Haugerud, Hidde D. Vuijk +1
Life relies on a sophisticated metabolic molecular machinery that turns over high-energy molecules to evolve complex macromolecules and assemblies. At the molecular origin of life,…
Excitability and oscillations of active droplets
Ivar S. Haugerud, Hidde D. Vuijk, Job Boekhoven +1
In living cells, cycles of formation and dissolution of liquid droplets can mediate biological functions such as DNA repair. However, the minimal physicochemical prerequisite for s…
Theory for sequence selection via phase separation and oligomerization
Ivar S. Haugerud, Giacomo Bartolucci, Dieter Braun +1
Non-equilibrium selection pressures were proposed for the formation of oligonucleotides with rich functionalities encoded in their sequences, such as catalysis. Since phase separat…