1 citations · 1 across the 1 of their papers we have counts for
3 papers
q-bio.BM2026★ 1 cited
Fold-switching proteins push the boundaries of conformational ensemble prediction
Myeongsang Lee, Lauren L. Porter
A protein's function depends critically on its conformational ensemble, a collection of energy weighted structures whose balance depends on temperature and environment. Though rece…
q-bio.BM2025
Fold-switching Proteins
Devlina Chakravarty, Lauren L. Porter
Globular proteins are expected to assume folds with fixed secondary structures, alpha-helices and beta-sheets. Fold-switching proteins challenge this expectation by remodeling thei…
q-bio.BM2024
Proteins with alternative folds reveal blind spots in AlphaFold-based protein structure prediction
Devlina Chakravarty, Myeongsang Lee, Lauren L. Porter
In recent years, advances in artificial intelligence (AI) have transformed structural biology, particularly protein structure prediction. Though AI-based methods, such as AlphaFold…