5 papers
Effect of Right Ventricular Outflow Tract Material Properties on Simulated Transcatheter Pulmonary Placement
Jalaj Maheshwari, Wensi Wu, Christopher N. Zelonis +9
Finite element (FE) simulations emulating transcatheter pulmonary valve (TPV) system deployment in patient-specific right ventricular outflow tracts (RVOT) assume material properti…
A geometric feature tracking approach for noninvasive patient specific estimation of leaflet strain from 3D images of heart valves
Wensi Wu, Matthew Daemer, Jeffrey A. Weiss +2
Valvular heart disease is prevalent and a major contributor to heart failure. Valve leaflet strain is a promising metric for evaluating the mechanics underlying the initiation and…
Simulation of Transcatheter Therapies for Atrioventricular Valve Regurgitation in an Open-Source Finite Element Simulation Framework
Seda Aslan, Nicolas R. Mangine, Devin W. Laurence +8
Purpose: Transcatheter edge-to-edge repair (TEER) and annuloplasty devices are increasingly used to treat mitral valve regurgitation, yet their mechanical effects and interactions…
Effect of Parametric Variation of Chordae Tendineae Structure on Simulated Atrioventricular Valve Closure
Nicolas R. Mangine, Devin W. Laurence, Patricia M. Sabin +9
Many approaches have been used to model chordae tendineae geometries in finite element simulations of atrioventricular heart valves. Unfortunately, current "functional" chordae ten…
ADEPT: A Noninvasive Method for Determining Elastic Parameters of Valve Tissue
Wensi Wu, Mitchell Daneker, Christian Herz +5
Computer simulation of "virtual interventions" may inform optimal valve repair for a given patient prior to intervention. However, the paucity of noninvasive methods to determine i…